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Research applications include studies of hepatic detoxification pathways, oxidative stress-related disease models, mitochondrial dysfunction, immune cell redox signaling, and skin depigmentation research (via inhibition of tyrosinase-mediated melanogenesis)

Oxidative stress promotes peroxiredoxin hyperoxidation and attenuates pro-survival signaling in aging chondrocytes

Traumatic brain injury causes an FK506-sensitive loss and an overgrowth of dendritic spines in rat forebrain

Several factors are at play: Aging: It is the most significant factor

Shreya et al., 2022)